ZHX3 Polyclonal Antibody
Ucallm_WP1966-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ZHX3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | ZHX3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ZHX3 KIAA0395 TIX1 |
| Protein Name | Zinc fingers and homeoboxes protein 3 (Triple homeobox protein 1) (Zinc finger and homeodomain protein 3) |
| Other Name | |
| Species | Human |
| Gene ID | 23051 |
| Uniprot | Q9H4I2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C0Q2, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q80Z36 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Widely expressed. High expression in kidney. Expressed during osteogenic differentiation. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Acts as a transcriptional repressor. Is a regulator of podocyte gene expression during primary glomerula disease.,similarity:Belongs to the ZHX family.,similarity:Contains 2 C2H2-type zinc fingers.,similarity:Contains 5 homeobox DNA-binding domains.,subunit:Forms homodimers. Also forms heterodimers with ZHX1 and ZHX2. Heterodimerization with ZHX1 is a prerequisite for repressor activity. Interacts with NFYA.,tissue specificity:Widely expressed. High expression in kidney., |
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