Name: ZIS Polyclonal Antibody
SKU: WP15059
Price: 268 USD
Availability: InStock

ZIS Polyclonal Antibody

Ucallm_WP15059-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP15059-100

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Product details

Background:

domain:The RanBP2-type zinc fingers mediate binding to RNA., function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5′-splice site selection., PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR., sequence caution:Intron retention., similarity:Belongs to the ZRANB2 family., similarity:Contains 2 RanBP2-type zinc fingers., subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,

Specifications

Target	ZIS
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	34kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human ZNF265. AA range:106-155
Sequence
Specificity	ZIS Polyclonal Antibody detects endogenous levels of ZIS protein.
Gene Name	ZRANB2
Protein Name	Zinc finger Ran-binding domain-containing protein 2
Other Name	ZRANB2; / ZIS; / ZNF265; / Zinc finger Ran-binding domain-containing protein 2; / Zinc finger protein 265; / Zinc finger; / splicing
Species	Human
Gene ID-1	9406
Uniprot	O95218,
Species.1	Mouse
Gene ID-2	53861
Uniprot.1	Q9R020,
Species.2	Rat
Gene ID-3	58821
Uniprot.2	O35986
Organism-4
Gene ID-4
SwissProt-4
Background	domain:The RanBP2-type zinc fingers mediate binding to RNA.,function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,
Cellular Localization	Nucleus .
Tissue Expression	Brain,Epithelium,Fetal brain,Fetal kidney,Liver,Skin,Testis,Uterus,
Signaling_pathway
Research Areas
Function	Domain:The RanBP2-type zinc fingers mediate binding to RNA.,Function:Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.,PTM:Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.,sequence Caution:Intron retention.,similarity:Belongs to the ZRANB2 family.,similarity:Contains 2 RanBP2-type zinc fingers.,subunit:Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of XE7 as well as with U2AF1 and CLK1.,
RRID

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ZIS Polyclonal Antibody

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ZIS Polyclonal Antibody

Product details

Specifications

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