Name: ZKSC1 rabbit pAb
SKU: WP3520
Price: 268 USD
Availability: InStock

ZKSC1 rabbit pAb

Ucallm_WP3520-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP3520-100

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Product details

Background:

The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010],

Specifications

Size	50μL/100μL
Target	ZKSC1
Reactivity	Human, Mouse, Rat
Applications	WB
MW(Calculated)
MW(Observed)	60kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human ZKSC1 AA range: 313-363
Specificity	This antibody detects endogenous levels of ZKSC1 at Human/Mouse/Rat
Gene Name	ZKSCAN1 KOX18 ZNF139 ZNF36
Protein Name	ZKSC1
Other Name	Zinc finger protein with KRAB and SCAN domains 1; / Zinc finger protein 139; / Zinc finger protein 36; / Zinc finger protein KOX18
Species	Human
Gene ID	7586
Uniprot	P17029,
Species.1	Mouse
Gene ID.1	74570
Uniprot.1	Q8BGS3,
Species.2	Rat
Gene ID.2	498160
Uniprot.2	Q4KLI1
Cellular Localization	Nucleus .
Tissue Expression	Brain,Epithelium,Eye,Fetal kidney,Insulinoma,Lung,Lymphoid,Pancreas,Spleen,
Signaling_pathway
Research Areas
Function	Function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 6 C2H2-type zinc fingers.,