SKU: WP15378 Categories: ,

ZKSCAN4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15378-100
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Product details

Background:

function:May be involved in the transcriptional activation of MDM2 and EP300 genes., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the krueppel C2H2-type zinc-finger protein family., similarity:Contains 1 KRAB domain., similarity:Contains 1 SCAN box domain., similarity:Contains 7 C2H2-type zinc fingers., tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.,

Specifications

Size50μL/100μL
TargetZKSCAN4
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)61kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from the Internal region of human ZKSCAN4.
SpecificityZKSCAN4 Polyclonal Antibody detects endogenous levels of ZKSCAN4 protein.
Gene NameZKSCAN4
Protein NameZinc finger protein with KRAB and SCAN domains 4
Other NameZKSCAN4; / ZNF307; / ZNF427; / Zinc finger protein with KRAB and SCAN domains 4; / P373c6.1; / Zinc finger protein 307; / Zinc finger protein 427
SpeciesHuman
Gene ID387032
UniprotQ969J2
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionExpressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.
Signaling_pathway
Research Areas
FunctionFunction:May be involved in the transcriptional activation of MDM2 and EP300 genes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 7 C2H2-type zinc fingers.,tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.,
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