Phospho-SMAD2 (Ser250) Rabbit Monoclonal Antibody

Background：The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.

Looking for a highly specific, rigorously validated Phospho-SMAD2 (Ser250) Rabbit Monoclonal Antibody? This Smad2 Phospho Ser250 antibody (Cat#: PT0058R; WR4011) is designed specifically for TGF-beta signaling pathway research. It accurately mediates experiments related to cell proliferation, apoptosis, and differentiation, and has been validated in 14 human/mouse/rat cell lines (including HL60, HUVEC, HCT116, etc.). It stably recognizes the 58 kDa target protein—with complete consistency between the predicted and observed band sizes. In Western Blot experiments, efficient binding can be achieved with a 1:2500 dilution and incubation at 4°C overnight, with no non-specific interference.

What’s more, it comes with supporting reagents to meet your one-stop experimental needs: 0.22 μm Nitrocellulose Membrane (Cat#: WSN21), 10-250 kDa Pre-stained Standard Protein Marker (Cat#: W2101), and Light 800-conjugated Goat anti-Rabbit Secondary Antibody (Cat#: WS0446). Whether you search for “TGF-beta signaling pathway research antibody”, “58 kDa target protein detection antibody”, or “Smad2 antibody validated in multiple cell lines”, this rabbit monoclonal antibody is the top choice for your Western Blot experiments. Search for “Phospho-SMAD2 (Ser250) Rabbit Monoclonal Antibody” or Cat# PT0058R; WR4011 to get product details instantly and accelerate your cellular signaling mechanism research!