Background:The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
Elevate your IGF-1 receptor (IGF1R) signaling and cancer research with the highly specific IGF1 Receptor Rabbit Monoclonal Antibody. Validated across diverse cell lines and optimized for Western Blot, it’s the trusted tool for investigating IGF1R-mediated cell growth regulation, oncogenic signaling pathways, and tumor progression mechanisms. Accelerate discoveries in oncology and cell growth biology with this top-tier antibody today!
Leave a Comment
Your email address will not be published. Required fields are marked *