SKU: WR4040 Categories: ,

U-Blot® LAMP1 Rabbit mAb

Price range: $268.00 through $328.00

SKU: WR4040-50
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Product details

Background:The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetLAMP1
ReactivityHuman
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)45kD
MW(Observed)110kD
Host SpeciesRabbit
IsotypeIgG,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:200-1:1000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
PurificationRecombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone NumberRM0104R
ImmunogenThe specific immunogen used to produce this antibody is proprietary information.
SpecificityEndogenous
Gene NameLAMP1
Protein NameLysosome-associated membrane glycoprotein 1
Other NameLAMP1; / Lysosome-associated membrane glycoprotein 1; / LAMP-1; / Lysosome-associated membrane protein 1; / CD107 antigen-like family member A; / CD107a
SpeciesHuman
Gene ID3916
UniprotP11279,
Species.1Mouse
Gene ID.1
Uniprot.1P11438,
Species.2Rat
Gene ID.225328
Uniprot.2P14562
Cellular LocalizationMembrane
Tissue ExpressionBrain,Liver,Pancreas,Placenta,Plasma,Testis,
Signaling_pathwayCellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Transport and catabolism >> Lysosome;Cellular Processes >> Transport and catabolism >> Autophagy - animal
Research Areas>>Autophagy - animal; / >>Lysosome; / >>Phagosome; / >>Tuberculosis
FunctionFunction:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,
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