SKU: WM0204 Categories: ,

Fucokinase Monoclonal Antibody

Price range: $268.00 through $328.00

SKU: WM0204-50
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Product details

Background:
fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetFucokinase
ReactivityHuman, Mouse, Rat, Monkey
ApplicationsWB, FC, ELISA
MW(Calculated)118kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; Flow Cyt 1:200-1:400; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationAffinity purification
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number12C2
ImmunogenPurified recombinant fragment of human Fucokinase expressed in E. Coli.
SpecificityFucokinase Monoclonal Antibody detects endogenous levels of Fucokinase protein.
Gene NameFUK
Protein NameL-fucose kinase
Other NameFUK; / L-fucose kinase; / Fucokinase
SpeciesHuman
Gene ID197258
UniprotQ8N0W3
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localizationcytoplasm,cytosol,
Tissue ExpressionExpressed in fibroblasts.
Signaling_pathway
Research Areas>>Fructose and mannose metabolism; / >>Amino sugar and nucleotide sugar metabolism; / >>Metabolic pathways; / >>Biosynthesis of nucleotide sugars
FunctionCatalytic activity:ATP + L-fucose = ADP + beta-L-fucose 1-phosphate.,Function:Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.,similarity:Belongs to the GHMP kinase family.,
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