Specifications
| Size | 50μL/100μL |
| Target | ST6GAL1 |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 47kD |
| MW(Observed) | 50-60kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM1760R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | ST6GAL1 SIAT1 |
| Protein Name | Beta-galactoside alpha-2,6-sialyltransferase 1 |
| Other Name | ST6GAL1; / SIAT1; / Beta-galactoside alpha-2; / 6-sialyltransferase 1; / Alpha 2,6-ST 1; / B-cell antigen CD75; / CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; / ST6Gal I; / ST6GalI; / Sialyltransferase 1 |
| Species | Human |
| Gene ID | 6480 |
| Uniprot | P15907, |
| Species.1 | Mouse |
| Gene ID.1 | 20440 |
| Uniprot.1 | Q64685, |
| Species.2 | Rat |
| Gene ID.2 | 25197 |
| Uniprot.2 | P13721 |
| Cellular Localization | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein . Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. |
| Tissue Expression | Liver,Lymph,Placenta,Skin,Spleen,Thymus, |
| Signaling_pathway | |
| Research Areas | >>N-Glycan biosynthesis; / >>Other types of O-glycan biosynthesis; / >>Metabolic pathways |
| Function | Catalytic activity:CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-2,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine.,Function:Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.,online information:GlycoGene database,online information:ST6Gal I,pathway:Protein modification; protein glycosylation.,PTM:The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 29 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid., |
