Specifications
| Size | 50μL/100μL |
| Target | ERK 1/2 Phospho Thr202/Tyr204 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 44/42kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | phosphate |
| Recommended Dilution Ratio | WB 1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 9A3 |
| Immunogen | Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) synthetic peptide conjugated to KLH. |
| Specificity | This antibody detects endogenous levels of Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) only when phosphorylated at Thr202 or Tyr204,and dually phosphorylated at two sites. |
| Gene Name | MAPK1/MAPK3 |
| Protein Name | |
| Other Name | ERK 1; / ERK 2; / ERK-2; / ERK1; / erk1/2; / ERK2; / ERT1; / ERT2; / Extracellular signal regulated kinase 1; / Extracellular signal regulated kinase 1; / Extracellular signal regulated kinase 2; / Extracellular signal regulated kinase 2; / Extracellular signal-regulated kinase 2; / HS44KDAP; / HUMKER1A; / Insulin stimulated MAP2 kinase; / MAP kinase 1; / MAP kinase 2; / MAP kinase isoform p42; / MAP kinase isoform p44; / MAPK 1; / MAPK 2; / MAPK 3; / MAPK 3; / MAPK1; / MAPK2; / MAPK3; / MGC20180; / Microtubule associated protein 2 kinase; / Mitogen activated protein kinase 1; / Mitogen activated protein kinase 1; / Mitogen activated protein kinase 2; / Mitogen activated protein kinase 3; / Mitogen activated protein kinase 3; / Mitogen-activated protein kinase 1; / Mitogen-activated protein kinase 2; / MK01_HUMAN; / p38; / p40; / p41; / p41mapk; / p42 MAPK; / p42-MAPK; / p42MAPK; / p42MAPK; / p44 ERK1; / p44 MAPK; / p44ERK1; / p44ERK1; / p44MAPK; / p44MAPK; / PRKM 1; / PRKM 1; / PRKM 2; / PRKM 2; / PRKM 3; / PRKM 3; / PRKM1; / PRKM2; / PRKM3; / Protein kinase mitogen activated 1; / Protein kinase mitogen activated 1; / Protein kinase mitogen activated 2; / Protein kinase mitogen activated 2; / Protein kinase mitogen activated 3; / Protein kinase mitogen activated 3; / Protein tyrosine kinase ERK 2; / Protein tyrosine kinase ERK 2. |
| Species | Human |
| Gene ID | 5594;5595 |
| Uniprot | P27361;P28482, |
| Species.1 | Mouse |
| Gene ID.1 | 26417;26413, |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 50689;116590 |
| Uniprot.2 | P21708;P63086 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Cellular Processes >> Cell growth and death >> Apoptosis;Cellular Processes >> Cell growth and death >> Cellular senescence;Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion;Cellular Processes >> Cellular community - eukaryotes >> Adherens junction;Cellular Processes >> Cellular community - eukaryotes >> Gap junction;Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells;Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton;Organismal Systems >> Immune system >> Platelet activation;Organismal Systems >> Immune system >> Neutrophil extracellular trap formation;Organismal Systems >> Immune system >> Toll-like receptor signaling pathway;Organismal Systems >> Immune system >> NOD-like receptor signaling pathway;Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity;Organismal Systems >> Immune system >> T cell receptor signaling pathway;Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation;Organismal Systems >> Immune system >> Th17 cell differentiation;Organismal Systems >> Immune system >> IL-17 signaling pathway;Organismal Systems >> Immune system >> B cell receptor signaling pathway;Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway;Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis;Organismal Systems >> Immune system >> Chemokine signaling pathway;Organismal Systems >> Endocrine system >> Insulin signaling pathway;Organismal Systems >> Endocrine system >> GnRH signaling pathway;Organismal Systems >> Endocrine system >> Estrogen signaling pathway;Organismal Systems >> Endocrine system >> Prolactin signaling pathway;Organismal Systems >> Endocrine system >> Oxytocin signaling pathway;Organismal Systems >> Endocrine system >> Relaxin signaling pathway;Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action;Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction;Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Cholinergic synapse;Organismal Systems >> Nervous system >> Neurotrophin signaling pathway;Organismal Systems >> Development and regeneration >> Osteoclast differentiation;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: overview >> MicroRNAs in cancer;Human Diseases >> Cancer: overview >> Central carbon metabolism in cancer;Human Diseases >> Cancer: overview >> PD-L1 expression and PD-1 checkpoint pathway in cancer;Human Diseases >> Cancer: specific types >> Colorectal cancer;Human Diseases >> Cancer: specific types >> Pancreatic cancer;Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma;Human Diseases >> Cancer: specific types >> Gastric cancer;Human Diseases >> Cancer: specific types >> Glioma;Human Diseases >> Cancer: specific types >> Thyroid cancer;Human Diseases >> Cancer: specific types >> Acute myeloid leukemia;Human Diseases >> Cancer: specific types >> Chronic myeloid leukemia;Human Diseases >> Cancer: specific types >> Melanoma;Human Diseases >> Cancer: specific types >> Renal cell carcinoma;Human Diseases >> Cancer: specific types >> Bladder cancer;Human Diseases >> Cancer: specific types >> Prostate cancer;Human Diseases >> Cancer: specific types >> Endometrial cancer;Human Diseases >> Cancer: specific types >> Breast cancer;Human Diseases >> Cancer: specific types >> Non-small cell lung cancer;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway;Environmental Information Processing >> Signal transduction >> ErbB signaling pathway;Environmental Information Processing >> Signal transduction >> Ras signaling pathway;Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway;Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway;Environmental Information Processing >> Signal transduction >> VEGF signaling pathway;Environmental Information Processing >> Signal transduction >> Apelin signaling pathway;Environmental Information Processing >> Signal transduction >> TNF signaling pathway;Environmental Information Processing >> Signal transduction >> HIF-1 signaling pathway;Environmental Information Processing >> Signal transduction >> FoxO signaling pathway;Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway;Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway;Environmental Information Processing >> Signal transduction >> cAMP signaling pathway;Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signal transduction >> mTOR signaling pathway |
| Research Areas | |
| Function |
