SKU: WP2785 Categories: ,

FABP6 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2785-100
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Product details

Background:

This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetFABP6
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)14kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 30-110
SpecificityFABP6 Polyclonal Antibody detects endogenous levels of protein.
Gene NameFABP6 ILBP ILLBP
Protein NameGastrotropin (GT) (Fatty acid-binding protein 6) (Ileal lipid-binding protein) (ILBP) (Intestinal 15 kDa protein) (I-15P) (Intestinal bile acid-binding protein) (I-BABP)
Other Name
SpeciesHuman
Gene ID2172
UniprotP51161,
Species.1Mouse
Gene ID.1
Uniprot.1P51162,
Species.2Rat
Gene ID.2
Uniprot.2P80020
Cellular Localization[Isoform 1]: Cytoplasm . Membrane; Peripheral membrane protein; Cytoplasmic side .; [Isoform 2]: Cytoplasm . Localized close to nucleus on the apical side of both normal and neoplastic cells. .
Tissue ExpressionIsoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level).
Signaling_pathwayOrganismal Systems >> Endocrine system >> PPAR signaling pathway
Research Areas>>PPAR signaling pathway
FunctionDomain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,Function:Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
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