SKU: WP4451 Categories: ,

TSSP rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4451-100
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Product details

Background:

This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetTSSP
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)57kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TSSP AA range: 50-100
SpecificityThis antibody detects endogenous levels of TSSP at Human/Mouse
Gene NamePRSS16 TSSP
Protein NameTSSP
Other Name
SpeciesHuman
Gene ID10279
UniprotQ9NQE7,
Species.1Mouse
Gene ID.154373
Uniprot.1Q9QXE5
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasmic vesicle. Vesicular, either lysosomal or endosomal.
Tissue ExpressionExpressed predominantly in cortical thymic epithelial cells.
Signaling_pathway
Research Areas
Functiondevelopmental stage:Expressed in fetal thymus.,Function:Protease that may play a role in T-cell development.,similarity:Belongs to the peptidase S28 family.,subcellular location:Vesicular, either lysosomal or endosomal.,tissue specificity:Expressed predominantly in cortical thymic epithelial cells.,
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