SKU: WP4551 Categories: ,

GLTL5 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4551-100
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Product details

Background:

Specifications

TargetGLTL5
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)49kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human GLTL5 AA range: 79-129
Sequence
SpecificityThis antibody detects endogenous levels of GLTL5 at Human/Mouse
Gene NameGALNTL5 GALNT15
Protein NameGLTL5
Other Name
SpeciesHuman
Gene ID-1168391
UniprotQ7Z4T8,
Species.1Mouse
Gene ID-267909
Uniprot.1Q9D4M9
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationLate endosome membrane; Single-pass type II membrane protein . Localizes to the juxtanuclear region, possibly the late endosome. Not localized in the Golgi apparatus in round spermatids (By similarity). .
Tissue ExpressionMainly expressed in testis. Weakly or not expressed in other tissues.
Signaling_pathway
Research Areas>>Mucin type O-glycan biosynthesis; / >>Other types of O-glycan biosynthesis; / >>Metabolic pathways
FunctionCaution:In contrast to other members of the family, it lacks the C-terminal ricin B-type lectin domain, which contributes to the glycopeptide specificity. Its precise function is therefore unsure.,cofactor:Calcium.,cofactor:Manganese.,Domain:There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.,Function:May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.,online information:GlycoGene database,online information:Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.,tissue specificity:Expressed in testis.,
RRID
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