Product details
Background:
DIO1 rabbit pAb
Ucallm_WP6137-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | DIO1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 27kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human DIO1 |
| Specificity | This antibody detects endogenous levels of DIO1 at Human, Mouse,Rat |
| Gene Name | DIO1 ITDI1 TXDI1 |
| Protein Name | Type I iodothyronine deiodinase (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) |
| Other Name | |
| Species | Human |
| Gene ID | 1733 |
| Uniprot | P49895, |
| Species.1 | Mouse |
| Gene ID.1 | 13370 |
| Uniprot.1 | Q61153, |
| Species.2 | Rat |
| Gene ID.2 | 25430 |
| Uniprot.2 | P24389 |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway |
| Research Areas | |
| Function | Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney. |
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