Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TRIM46
Specificity
This antibody detects endogenous levels of TRIM46 at Human, Mouse
Gene Name
TRIM46 TRIFIC
Protein Name
Tripartite motif-containing protein 46 (Gene Y protein) (GeneY) (Tripartite, fibronectin type-III and C-terminal SPRY motif protein)
Other Name
Species
Human
Gene ID
80128
Uniprot
Q7Z4K8,
Species.1
Mouse
Gene ID.1
360213
Uniprot.1
Q7TNM2
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell projection, axon . Cytoplasm, cytoskeleton . Microtubule-associated. Localizes to the proximal part of the axon. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Microtubule-associated protein that is involved in the formation of parallel microtubule bundles linked by cross-bridges in the proximal axon. Required for the uniform orientation and maintenance of the parallel microtubule fascicles, which are important for efficient cargo delivery and trafficking in axons. Thereby also required for proper axon specification, the establishment of neuronal polarity and proper neuronal migration.