Name: TrpRS rabbit pAb
SKU: WP7152
Price: 268 USD
Availability: InStock

TrpRS rabbit pAb

Ucallm_WP7152-50

Price range: $268.00 through $328.00

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SKU: WP7152-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	WARS1
Reactivity	Human, Mouse, Rat
Applications	WB
MW(Calculated)	52kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human TrpRS
Specificity	This antibody detects endogenous levels of TrpRS at Human, Mouse,Rat
Gene Name	WARS IFI53 WRS
Protein Name	Tryptophan--tRNA ligase, cytoplasmic (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS]
Other Name
Species	Human
Gene ID	7453
Uniprot	P23381,
Species.1	Mouse
Gene ID.1	22375
Uniprot.1	P32921,
Species.2	Rat
Gene ID.2
Uniprot.2	Q6P7B0
Cellular Localization	Cytoplasm.
Tissue Expression
Signaling_pathway
Research Areas
Function	Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

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