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TRPM6 rabbit pAb
Ucallm_WP7645-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TRPM6 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 222kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TRPM6 |
| Specificity | This antibody detects endogenous levels of TRPM6 at Human, Mouse |
| Gene Name | TRPM6 CHAK2 |
| Protein Name | Transient receptor potential cation channel subfamily M member 6 (Channel kinase 2) (Melastatin-related TRP cation channel 6) |
| Other Name | |
| Species | Human |
| Gene ID | 140803 |
| Uniprot | Q9BX84, |
| Species.1 | Mouse |
| Gene ID.1 | 225997 |
| Uniprot.1 | Q8CIR4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Expression | Highly expressed in kidney and colon. Isoform TRPM6a and isoform TRPM6b, are coexpressed with TRPM7 in kidney, and testis, and are also found in several cell lines of lung origin. Isoform TRPM6c is detected only in testis and in NCI-H510A small cell lung carcinoma cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region. |
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