Name: TPMT rabbit pAb
SKU: WP7155
Price: 268 USD
Availability: InStock

TPMT rabbit pAb

Ucallm_WP7155-50

Price range: $268.00 through $328.00

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SKU: WP7155-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	TPMT
Reactivity	Human, Mouse, Rat
Applications	WB
MW(Calculated)	27kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human TPMT
Specificity	This antibody detects endogenous levels of TPMT at Human, Mouse,Rat
Gene Name	TPMT
Protein Name	Thiopurine S-methyltransferase (Thiopurine methyltransferase)
Other Name
Species	Human
Gene ID	7172
Uniprot	P51580,
Species.1	Mouse
Gene ID.1	22017
Uniprot.1	O55060,
Species.2	Rat
Gene ID.2
Uniprot.2	Q9Z0T0
Cellular Localization	Cytoplasm.
Tissue Expression
Signaling_pathway
Research Areas
Function	Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S-adenosyl-L-methionine as the methyl donor . TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified.