Product details
Background:
Background:
| Size | 50μL/100μL |
| Target | IFT56 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 61kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TTC26 |
| Specificity | This antibody detects endogenous levels of TTC26 at Human, Mouse,Rat |
| Gene Name | TTC26 |
| Protein Name | Tetratricopeptide repeat protein 26 (TPR repeat protein 26) |
| Other Name | |
| Species | Human |
| Gene ID | 79989 |
| Uniprot | A0AVF1, |
| Species.1 | Mouse |
| Gene ID.1 | 264134 |
| Uniprot.1 | Q8BS45, |
| Species.2 | Rat |
| Gene ID.2 | 500086 |
| Uniprot.2 | Q5U2N8 |
| Cellular Localization | Cell projection, cilium . Localizes at the base to the ciliary transition zone. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI2 and GLI3 at the ciliary tips and their dissociation from the negative regulator SUFU. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Not required for IFT complex A ciliary localization or function. Essential for maintaining proper microtubule organization within the ciliary axoneme. |