Product details
Background:
MMADHC rabbit pAb
Ucallm_WP7886-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MMADHC |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 33kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MMADHC |
| Specificity | This antibody detects endogenous levels of MMADHC at Human, Mouse,Rat |
| Gene Name | MMADHC C2orf25 CL25022 HSPC161 My011 |
| Protein Name | Methylmalonic aciduria and homocystinuria type D protein, mitochondrial |
| Other Name | |
| Species | Human |
| Gene ID | 27249 |
| Uniprot | Q9H3L0, |
| Species.1 | Mouse |
| Gene ID.1 | 109129 |
| Uniprot.1 | Q99LS1, |
| Species.2 | Rat |
| Gene ID.2 | 362134 |
| Uniprot.2 | Q6AYQ6 |
| Cellular Localization | Cytoplasm . Mitochondrion . |
| Tissue Expression | Widely expressed at high levels. |
| Signaling_pathway | |
| Research Areas | |
| Function | Involved in cobalamin metabolism and trafficking . Plays a role in regulating the biosynthesis and the proportion of two coenzymes, methylcob(III)alamin (MeCbl) and 5'-deoxyadenosylcobalamin (AdoCbl) . Promotes oxidation of cob(II)alamin bound to MMACHC . The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR (methionine synthase) which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine . |
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