Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TMTC1
Specificity
This antibody detects endogenous levels of TMTC1 at Human, Mouse
Gene Name
TMTC1 ARG99
Protein Name
Transmembrane and TPR repeat-containing protein 1
Other Name
Species
Human
Gene ID
83857
Uniprot
Q8IUR5,
Species.1
Mouse
Gene ID.1
387314
Uniprot.1
Q3UV71
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Membrane; Multi-pass membrane protein . Endoplasmic reticulum .
Tissue Expression
Signaling_pathway
Research Areas
Function
Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.