Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C21orf59
Specificity
This antibody detects endogenous levels of C21orf59 at Human
Gene Name
C21orf59 C21orf48
Protein Name
Uncharacterized protein C21orf59
Other Name
Species
Human
Gene ID
56683
Uniprot
P57076
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Cytoplasm, cytoskeleton, cilium basal body . Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly . Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity).