SKU: WP9543 Categories: ,

Annexin II (phospho Ser26) Polyclonal Antibody

Price range: $288.00 through $368.00

SKU: WP9543-100
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Product details

Background:

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Specifications

TargetAnnexin II
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)38kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationPhospho
Recommended Dilution RatioWB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized phospho-peptide around the phosphorylation site of human Annexin II (phospho Ser26)
Sequence
SpecificityPhospho-Annexin II (S26) Polyclonal Antibody detects endogenous levels of Annexin II protein only when phosphorylated at S26.
Gene NameANXA2
Protein NameAnnexin A2
AliasANXA2;ANX2;ANX2L4;CAL1H;LPC2D;Annexin A2;Annexin II;Annexin-2;Calpactin I heavy chain;Calpactin-1 heavy chain;Chromobindin-8;Lipocortin II;Placental anticoagulant protein IV;PAP-IV;Protein I;p36
Organism-1Human
Gene ID-1302
SwissProt-1P07355
Organism-2Mouse
Gene ID-212306
SwissProt-2P07356
Organism-3Rat
Gene ID-356611
SwissProt-3Q07936
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationSecreted, extracellular space, extracellular matrix, basement membrane . Melanosome . In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
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