Price range: $268.00 through $328.00
Background:
This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | ALX3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 36kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ALX3. AA range:171-220 |
| Specificity | ALX3 Polyclonal Antibody detects endogenous levels of ALX3 protein. |
| Gene Name | ALX3 |
| Protein Name | Homeobox protein aristaless-like 3 |
| Other Name | ALX3; / Homeobox protein aristaless-like 3; / Proline-rich transcription factor ALX3 |
| Species | Human |
| Gene ID | 257 |
| Uniprot | O95076, |
| Species.1 | Mouse |
| Gene ID.1 | 11694 |
| Uniprot.1 | O70137 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Brain,Neuroblastoma, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcriptional regulator with a possible role in patterning of mesoderm during development.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
