SKU: WP12915 Categories: ,

Keratin 37/38 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12915-100
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Product details

Background:

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetKeratin 37/38
ReactivityHuman
ApplicationsWB, ELISA, IHC
MW(Calculated)
MW(Observed)50kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human KRT37/38. AA range:201-250
SpecificityKeratin 37/38 Polyclonal Antibody detects endogenous levels of Keratin 37/38 protein.
Gene NameKRT37/KRT38
Protein NameKeratin type I cuticular Ha7/Keratin type I cuticular Ha8
Other NameKRT37; / HHA7; / HKA7; / KRTHA7; / Keratin; / type I cuticular Ha7; / Hair keratin, type I Ha7; / Keratin-37; / K37; / KRT38; / HHA8; / HKA8; / KRTHA8; / Keratin, type I cuticular Ha8; / Hair keratin, type I Ha8; / Keratin-38; / K38
SpeciesHuman
Gene ID8688
UniprotO76014;O76015
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localizationintermediate filament,extracellular exosome,
Tissue ExpressionScalp,
Signaling_pathwayOrganismal Systems >> Endocrine system >> Estrogen signaling pathway
Research Areas>>Estrogen signaling pathway; / >>Staphylococcus aureus infection
Functionmiscellaneous:There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).,similarity:Belongs to the intermediate filament family.,
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