SKU: WP14554 Categories: ,

Spectrin β V Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14554-100
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Product details

Background:

similarity:Belongs to the spectrin family., similarity:Contains 1 PH domain., similarity:Contains 2 CH (calponin-homology) domains., similarity:Contains 31 spectrin repeats., subcellular location:Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells., subunit:Probably associates with an alpha chain., tissue specificity:Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.,

Specifications

Size50μL/100μL
TargetSpectrin β V
ReactivityHuman
ApplicationsIHC, IF, ELISA
MW(Calculated)417kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human SPTBN5. AA range:481-530
SpecificitySpectrin β V Polyclonal Antibody detects endogenous levels of Spectrin β V protein.
Gene NameSPTBN5
Protein NameSpectrin beta chain non-erythrocytic 5
Other NameSPTBN5; / BSPECV; / HUBSPECV; / HUSPECV; / Spectrin beta chain; / non-erythrocytic 5; / Beta-V spectrin
SpeciesHuman
Gene ID51332
UniprotQ9NRC6
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton. Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.
Tissue ExpressionExpressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 2 CH (calponin-homology) domains.,similarity:Contains 31 spectrin repeats.,subcellular location:Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.,subunit:Probably associates with an alpha chain.,tissue specificity:Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.,
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