Price range: $268.00 through $328.00
Background:
This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],
| Size | 50μL/100μL |
| Target | Tra-2α |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 33kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TRA-2 alpha. AA range:221-270 |
| Specificity | Tra-2α Polyclonal Antibody detects endogenous levels of Tra-2α protein. |
| Gene Name | TRA2A |
| Protein Name | Transformer-2 protein homolog alpha |
| Other Name | TRA2A; / Transformer-2 protein homolog alpha; / TRA-2 alpha; / TRA2-alpha; / Transformer-2 protein homolog A |
| Species | Human |
| Gene ID | 29896 |
| Uniprot | Q13595, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6PFR5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Cervix carcinoma,Epithelium,Hepatocyte,Lung,Testis,Uterus, |
| Signaling_pathway | |
| Research Areas | >>Spliceosome; / >>Alcoholic liver disease |
| Function | Function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.,PTM:Phosphorylated in the RS domains.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30., |
