SKU: WP14907 Categories: ,

TWIK-3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14907-100
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Product details

Background:

This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetTWIK-3
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)32kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from TWIK-3 . at AA range: 170-250
SpecificityTWIK-3 Polyclonal Antibody detects endogenous levels of TWIK-3 protein.
Gene NameKCNK7
Protein NamePotassium channel subfamily K member 7
Other NameKCNK7; / Potassium channel subfamily K member 7
SpeciesHuman
Gene ID10089
UniprotQ9Y2U2,
Species.1Mouse
Gene ID.1
Uniprot.1Q9Z2T1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Multi-pass membrane protein .
Tissue ExpressionBrain,PCR rescued clones,
Signaling_pathway
Research Areas
FunctionFunction:Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
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