Price range: $268.00 through $328.00
Background:
function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity., similarity:Belongs to the G-protein coupled receptor 1 family.,
| Size | 50μL/100μL |
| Target | SR-1D |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 41kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from SR-1D . at AA range: 120-200 |
| Specificity | SR-1D Polyclonal Antibody detects endogenous levels of SR-1D protein. |
| Gene Name | HTR1D |
| Protein Name | 5-hydroxytryptamine receptor 1D |
| Other Name | HTR1D; / HTR1DA; / HTRL; / 5-hydroxytryptamine receptor 1D; / 5-HT-1D; / 5-HT1D; / 5-HT-1D-alpha; / Serotonin receptor 1D |
| Species | Human |
| Gene ID | 3352 |
| Uniprot | P28221, |
| Species.1 | Mouse |
| Gene ID.1 | 15552 |
| Uniprot.1 | Q61224, |
| Species.2 | Rat |
| Gene ID.2 | 25323 |
| Uniprot.2 | P28565 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Detected in brain neocortex and caudate nucleus (at protein level). |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> cAMP signaling pathway |
| Research Areas | >>cAMP signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Serotonergic synapse; / >>Taste transduction |
| Function | Function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 1 family., |
