Background:The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5′-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
If you’re researching cellular energy sensing, metabolic enzyme regulation, or cell protection against ATP-depleting stress—you need an AMPK α1 antibody that’s consistent across your experiments.The AMPK α1 Rabbit Monoclonal Antibody (WR4079) delivers exactly that: it’s validated across 14 human/mouse/rat cell lines (HL60, HUVEC, HCT116, and more), so you never waste time troubleshooting cell-specific signal drops. Its 1:2500 dilution ratio cuts reagent costs without weakening detection.
Most critically, it hits the precise 64 kDa band (predicted = observed)—ensuring you’re detecting the functional AMPK α1 subunit that drives energy homeostasis and metabolic enzyme regulation (the core of your research focus).Search “AMPK α1 Rabbit Monoclonal Antibody WR4079” or “AMPK α1 antibody for cellular energy sensor & metabolic regulation” to access the product page: grab optimized protocols, request a trial sample, and advance your AMPK α1 studies without antibody-related delays.
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