Background：This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Elevate your reactive oxygen species (ROS) and NOX4 research with the NOX4 Rabbit Monoclonal Antibody (WR4092)—a Google-optimized, rigorously validated tool for specific NOX4 detection. Tested across 14+ human, mouse, and rat cell lines (HL60, HCT116, HUVEC, etc.), this antibody delivers perfect band alignment (67 kDa predicted/observed) via 4-20% SDS-PAGE, paired with optimized conditions (4°C overnight incubation, 1:2500 dilution) and a robust Dylight 800-conjugated detection system.
Ideal for studying NOX4’s role as the NADPH oxidase catalytic subunit, oxygen sensing, or ROS-mediated processes (signal transduction, cell differentiation, tumor growth), this trusted NOX4 Rabbit Monoclonal Antibody boosts assay reproducibility. Order WR4092 today to advance your NOX4-focused experiments with a SEO-verified, high-performance research tool tailored for oxidative stress and cancer biology studies.`
Leave a Comment
Your email address will not be published. Required fields are marked *