NQO1 Rabbit Monoclonal antibody

Background：This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein’s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer’s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Elevate your cancer and Alzheimer’s disease research with the highly specific NQO1 Rabbit Monoclonal Antibody. Validated across diverse cell lines and optimized for Western Blot, it’s the go-to tool for investigating NQO1’s role as a quinone reductase in tumor biology and neurodegenerative pathways. Accelerate your discoveries in oncology and neuroscience with this reliable antibody today!