Price range: $268.00 through $328.00
Background:
alternative products:Experimental confirmation may be lacking for some isoforms, catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine., function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions., similarity:Belongs to the DNA glycosylase MPG family., subunit:Binds MBD1.,
| Size | 50μL/100μL |
| Target | 3MG |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | 3MG Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | MPG AAG ANPG MID1 |
| Protein Name | DNA-3-methyladenine glycosylase (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase) |
| Other Name | |
| Species | Human |
| Gene ID | 4350 |
| Uniprot | P29372, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q04841, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P23571 |
| Cellular Localization | Cytoplasm . Mitochondrion matrix, mitochondrion nucleoid . Nucleus . |
| Tissue Expression | Epithelium,Liver,Pancreas, |
| Signaling_pathway | |
| Research Areas | >>Base excision repair |
| Function | Alternative products:Experimental confirmation may be lacking for some isoforms,Catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,Function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1., |
