Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human AADAC
Specificity
This antibody detects endogenous levels of AADAC at Human, Mouse,Rat
Gene Name
AADAC DAC
Protein Name
Arylacetamide deacetylase (EC 3.1.1.3)
Other Name
Species
Human
Gene ID
13
Uniprot
P22760,
Species.1
Mouse
Gene ID.1
67758
Uniprot.1
Q99PG0,
Species.2
Rat
Gene ID.2
57300
Uniprot.2
Q9QZH8
Cellular Localization
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.
Tissue Expression
Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder.
Signaling_pathway
Research Areas
Function
Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.