SKU: WP0902 Categories: ,

ABCB8 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0902-100
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Product details

Background:

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Specifications

Size50μL/100μL
TargetABCB8
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)80kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 510-590
SpecificityABCB8 Polyclonal Antibody detects endogenous levels of protein.
Gene NameABCB8 MABC1
Protein NameATP-binding cassette sub-family B member 8, mitochondrial (Mitochondrial ATP-binding cassette 1) (M-ABC1)
Other Name
SpeciesHuman
Gene ID11194
UniprotQ9NUT2,
Species.1Mouse
Gene ID.1
Uniprot.1Q9CXJ4,
Species.2Rat
Gene ID.2
Uniprot.2Q5RKI8
Cellular LocalizationMitochondrion inner membrane; Multi-pass membrane protein .
Tissue ExpressionUbiquitous.
Signaling_pathway
Research Areas>>ABC transporters
Functionsimilarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Monomer .,tissue specificity:Ubiquitous.,
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