Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ABI2 AA range: 61-111
Specificity
This antibody detects endogenous levels of human ABI2
Gene Name
ABI2 ARGBPIA
Protein Name
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Other Name
Species
Human
Gene ID
10152
Uniprot
Q9NYB9,
Species.1
Mouse
Gene ID.1
329165
Uniprot.1
P62484
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Nucleus .; [Isoform 1]: Cell projection, lamellipodium . Cell projection, filopodium . Cytoplasm, cytoskeleton . Cell junction, adherens junction . Isoform 1 but not isoform 3 is localized to protruding lamellipodia and filopodia tips (PubMed:11516653, PubMed:15572692). Present at nascent adherens junctions, where it clusters adjacent to the tips of F-actin protrusions (PubMed:15572692). .
Tissue Expression
Widely expressed. Abundant in testes, ovary, thymus, and colon, with lower but detectable levels in prostate, peripheral blood leukocytes, and spleen.
Signaling_pathway
Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton