Price range: $268.00 through $328.00
Background:
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010],
| Size | 50μL/100μL |
| Target | ABTB1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 53kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ABTB1 AA range: 163-213 |
| Specificity | This antibody detects endogenous levels of ABTB1 at Human/Mouse/Rat |
| Gene Name | ABTB1 BPOZ PP2259 |
| Protein Name | ABTB1 |
| Other Name | |
| Species | Human |
| Gene ID | 80325 |
| Uniprot | Q969K4, |
| Species.1 | Mouse |
| Gene ID.1 | 80283 |
| Uniprot.1 | Q99LJ2, |
| Species.2 | Rat |
| Gene ID.2 | 297432 |
| Uniprot.2 | Q5XIU1 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart., |
