Name: ACOD Polyclonal Antibody
SKU: WP3358
Price: 268 USD
Availability: InStock

ACOD Polyclonal Antibody

Ucallm_WP3358-50

Price range: $268.00 through $328.00

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100μl

50μl

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SKU: WP3358-100

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Product details

Background:

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015],

Specifications

Target	SCD
Reactivity	Human
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	39kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from part region of human protein
Sequence
Specificity	ACOD Polyclonal Antibody detects endogenous levels of protein.
Gene Name	SCD
Protein Name	Acyl-CoA desaturase (Delta(9)-desaturase) (Delta-9 desaturase) (Fatty acid desaturase) (Stearoyl-CoA desaturase)
Other Name
Species	Human
Gene ID-1	6319
Uniprot	O00767
Species.1
Gene ID-2
Uniprot.1
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015],
Cellular Localization	Endoplasmic reticulum membrane; Multi-pass membrane protein .
Tissue Expression	Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung.
Signaling_pathway	Organismal Systems >> Endocrine system >> PPAR signaling pathway;Environmental Information Processing >> Signal transduction >> AMPK signaling pathway
Research Areas	>>Biosynthesis of unsaturated fatty acids; / >>Metabolic pathways; / >>Fatty acid metabolism; / >>PPAR signaling pathway; / >>AMPK signaling pathway; / >>Alcoholic liver disease
Function	Catalytic activity:Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.,cofactor:Iron.,Domain:The histidine box domains may contain the active site and/or be involved in metal ion binding.,Function:Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.,similarity:Belongs to the fatty acid desaturase family.,
RRID

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ACOD Polyclonal Antibody

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ACOD Polyclonal Antibody

Product details

Specifications

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