Name: ADH4 rabbit pAb
SKU: WP3777
Price: 268 USD
Availability: InStock

ADH4 rabbit pAb

Ucallm_WP3777-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP3777-100

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Product details

Background:

This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008],

Specifications

Target	ADH4
Reactivity	Human, Mouse, Rat
Applications	WB
MW(Calculated)	42kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human ADH4 AA range: 6-56
Sequence
Specificity	This antibody detects endogenous levels of ADH4 at Human/Mouse/Rat
Gene Name	ADH4
Protein Name	ADH4
Other Name
Species	Human
Gene ID-1	127
Uniprot	P08319,
Species.1	Mouse
Gene ID-2	26876
Uniprot.1	Q9QYY9,
Species.2	Rat
Gene ID-3
Uniprot.2	Q64563
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008],
Cellular Localization	Cytoplasm.
Tissue Expression
Signaling_pathway
Research Areas	>>Glycolysis / Gluconeogenesis; / >>Fatty acid degradation; / >>Tyrosine metabolism; / >>Pyruvate metabolism; / >>Retinol metabolism; / >>Metabolism of xenobiotics by cytochrome P450; / >>Drug metabolism - cytochrome P450; / >>Metabolic pathways; / >>Alcoholic liver disease
Function	Catalytic activity:An alcohol + NAD(+) = an aldehyde or ketone + NADH.,cofactor:Binds 2 zinc ions per subunit.,miscellaneous:There are 7 different ADH's isozymes in human: three belongs to class-I: alpha, beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to class-V: ADH6.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Class-II subfamily.,subunit:Homodimer.,
RRID

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ADH4 rabbit pAb

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ADH4 rabbit pAb

Product details

Specifications

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