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AGTRAP rabbit pAb
Ucallm_WP6444-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AGTRAP |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 17kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AGTRAP |
| Specificity | This antibody detects endogenous levels of AGTRAP at Human, Mouse,Rat |
| Gene Name | AGTRAP ATRAP |
| Protein Name | Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein) |
| Other Name | |
| Species | Human |
| Gene ID | 57085 |
| Uniprot | Q6RW13, |
| Species.1 | Mouse |
| Gene ID.1 | 11610 |
| Uniprot.1 | Q9WVK0, |
| Species.2 | Rat |
| Gene ID.2 | 298646 |
| Uniprot.2 | Q642A2 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Golgi apparatus membrane; Multi-pass membrane protein . Cytoplasmic vesicle membrane; Multi-pass membrane protein . Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles. |
| Tissue Expression | Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. |
| Signaling_pathway | |
| Research Areas | |
| Function | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
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