Name: AKAP 110 Polyclonal Antibody
SKU: WP10992
Price: 268 USD
Availability: InStock

AKAP 110 Polyclonal Antibody

Ucallm_WP10992-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP10992-100

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Product details

Background:

This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction. [provided by RefSeq, May 2013],

Specifications

Size	50μL/100μL
Target	AKAP 110
Reactivity	Human, Mouse
Applications	IF, ELISA
MW(Calculated)	95kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications;
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human AKAP3. AA range:191-240
Specificity	AKAP 110 Polyclonal Antibody detects endogenous levels of AKAP 110 protein.
Gene Name	AKAP3
Protein Name	A-kinase anchor protein 3
Other Name	AKAP3; / AKAP110; / SOB1; / A-kinase anchor protein 3; / AKAP-3; / A-kinase anchor protein 110 kDa; / AKAP 110; / Cancer/testis antigen 82; / CT82; / Fibrous sheath protein of 95 kDa; / FSP95; / Fibrousheathin I; / Fibrousheathin-1; / Protein kinase A-anchoring prot
Species	Human
Gene ID	10566
Uniprot	O75969,
Species.1	Mouse
Gene ID.1	11642
Uniprot.1	O88987
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasmic vesicle, secretory vesicle, acrosome . Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.
Tissue Expression	Testis specific; only expressed in spermatids.
Signaling_pathway
Research Areas
Function	Domain:RII-binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,Function:May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the AKAP110 family.,subcellular location:Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.,subunit:Interacts with ROPN1 AND ROPN1L.,tissue specificity:Testis specific; only expressed in spermatids.,

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AKAP 110 Polyclonal Antibody

Product details

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AKAP 110 Polyclonal Antibody

Product details

Specifications

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