Name: Amylin Polyclonal Antibody
SKU: WP11042
Price: 268 USD
Availability: InStock

Amylin Polyclonal Antibody

Ucallm_WP11042-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP11042-100

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Product details

Background:

islet amyloid polypeptide(IAPP) Homo sapiens This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016],

Specifications

Size	50μL/100μL
Target	Amylin
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	25kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human Amylin. AA range:1-50
Specificity	Amylin Polyclonal Antibody detects endogenous levels of Amylin protein.
Gene Name	IAPP
Protein Name	Islet amyloid polypeptide
Other Name	IAPP; / Islet amyloid polypeptide; / Amylin; / Diabetes-associated peptide; / DAP; / Insulinoma amyloid peptide
Species	Human
Gene ID	3375
Uniprot	P10997,
Species.1	Mouse
Gene ID.1
Uniprot.1	P12968
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Secreted .
Tissue Expression
Signaling_pathway
Research Areas	>>Neuroactive ligand-receptor interaction; / >>Maturity onset diabetes of the young
Function	Disease:IAPP is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.,Function:Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.,online information:Amylin entry,similarity:Belongs to the calcitonin family.,