ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).[supplied by OMIM, Jan 2011],
Specifications
Size
50μL/100μL
Target
ANO2
Reactivity
Human, Mouse
Applications
WB
MW(Calculated)
110kD
MW(Observed)
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ANO2 AA range: 362-412
Specificity
This antibody detects endogenous levels of ANO2 at Human/Mouse
Gene Name
ANO2 C12orf3 TMEM16B
Protein Name
ANO2
Other Name
Species
Human
Gene ID
57101
Uniprot
Q9NQ90,
Species.1
Mouse
Gene ID.1
243634
Uniprot.1
Q8CFW1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell membrane; Multi-pass membrane protein .
Tissue Expression
Retina, especially in the photoreceptor synaptic terminals.
Signaling_pathway
Research Areas
>>Olfactory transduction
Function
Function:May act as a calcium-activated chloride channel.,similarity:Belongs to the anoctamin family.,