SKU: WP16937 Categories: ,

ALG13 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16937-100
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Product details

Background:

The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],

Specifications

Size50μL/100μL
TargetALG13
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)125kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ALG13 AA range: 69-119
SpecificityThis antibody detects endogenous levels of ALG13 at Human/Mouse/Rat
Gene NameALG13 CXorf45 GLT28D1 MDS031
Protein NameALG13
Other Name
SpeciesHuman
Gene ID79868
UniprotQ9NP73,
Species.1Mouse
Gene ID.167574
Uniprot.1Q9D8C3,
Species.2Rat
Gene ID.2300284
Uniprot.2Q5I0K7
Cellular Localization[Isoform 2]: Endoplasmic reticulum . Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14.
Tissue Expression
Signaling_pathway
Research Areas>>N-Glycan biosynthesis; / >>Various types of N-glycan biosynthesis; / >>Metabolic pathways
FunctionCatalytic activity:UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N'-diacetylchitobiosyl-diphosphodolichol.,Function:Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.,online information:GlycoGene database,similarity:Belongs to the glycosyltransferase 28 family.,subunit:Heterodimer with ALG14 to form a functional enzyme.,
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