SKU: WP7266 Categories: ,

AP3D1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7266-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetAP3D1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)127kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AP3D1
SpecificityThis antibody detects endogenous levels of AP3D1 at Human, Mouse
Gene NameAP3D1 PRO0039
Protein NameAP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin)
Other Name
SpeciesHuman
Gene ID8943
UniprotO14617,
Species.1Mouse
Gene ID.111776
Uniprot.1O54774
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side .
Tissue ExpressionPresent in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis.
Signaling_pathwayCellular Processes >> Transport and catabolism >> Lysosome
Research Areas
FunctionPart of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation . In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity).
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