SKU: WP0882 Categories: ,

AQP9 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0882-100
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Product details

Background:

The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue . The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Specifications

Size50μL/100μL
TargetAQP9
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)32kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 160-240
SpecificityAQP9 Polyclonal Antibody detects endogenous levels of protein.
Gene NameAQP9 SSC1
Protein NameAquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1)
Other Name
SpeciesHuman
Gene ID366
UniprotO43315,
Species.1Mouse
Gene ID.1
Uniprot.1Q9JJJ3,
Species.2Rat
Gene ID.2
Uniprot.2P56627
Cellular LocalizationCell membrane; Multi-pass membrane protein .
Tissue ExpressionHighly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.
Signaling_pathwayOrganismal Systems >> Immune system >> Neutrophil extracellular trap formation
Research Areas>>Neutrophil extracellular trap formation; / >>Bile secretion
FunctionDomain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,Function:Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea but not to glycerol.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.,
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