Price range: $268.00 through $328.00
Background:
This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
| Size | 50μL/100μL |
| Target | NR2F2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human COT2. AA range:1-50 |
| Specificity | ARP-1 Polyclonal Antibody detects endogenous levels of ARP-1 protein. |
| Gene Name | NR2F2 |
| Protein Name | COUP transcription factor 2 |
| Other Name | NR2F2; / ARP1; / TFCOUP2; / COUP transcription factor 2; / COUP-TF2; / Apolipoprotein A-I regulatory protein 1; / ARP-1; / COUP transcription factor II; / COUP-TF II; / Nuclear receptor subfamily 2 group F member 2 |
| Species | Human |
| Gene ID | 7026 |
| Uniprot | P24468, |
| Species.1 | Mouse |
| Gene ID.1 | 11819 |
| Uniprot.1 | P43135, |
| Species.2 | Rat |
| Gene ID.2 | 113984 |
| Uniprot.2 | O09018 |
| Cellular Localization | Nucleus. |
| Tissue Expression | Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with SQSTM1 (By similarity). Binds DNA as a homodimer.,tissue specificity:Found in all tissues., |
