SKU: WP11208 Categories: ,

ATP5S Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11208-100
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Product details

Background:

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetATP5S
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)23kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ATP5S. AA range:21-70
SpecificityATP5S Polyclonal Antibody detects endogenous levels of ATP5S protein.
Gene NameATP5S
Protein NameATP synthase subunit s mitochondrial
Other NameATP5S; / ATPW; / ATP synthase subunit s; / mitochondrial; / ATP synthase-coupling factor B; / FB; / Mitochondrial ATP synthase regulatory component factor B
SpeciesHuman
Gene ID27109
UniprotQ99766,
Species.1Mouse
Gene ID.168055
Uniprot.1Q9CRA7
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion . Mitochondrion inner membrane .
Tissue ExpressionBrain,Hippocampus,Uterus,
Signaling_pathway
Research Areas
FunctionCaution:It is uncertain whether Met-1 or Met-16 is the initiator.,Function:Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase.,similarity:Belongs to the ATP synthase subunit s family.,subunit:Monomer. Associates with ATP synthase.,
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