AVP Receptor V3 Polyclonal Antibody
Ucallm_WP11222-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | AVP Receptor V3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 47kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324 |
| Specificity | AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein. |
| Gene Name | AVPR1B AVPR3 VPR3 |
| Protein Name | Vasopressin V1b receptor |
| Other Name | AVPR1B; / AVPR3; / VPR3; / Vasopressin V1b receptor; / V1bR; / AVPR V1b; / AVPR V3; / Antidiuretic hormone receptor 1b; / Vasopressin V3 receptor |
| Species | Human |
| Gene ID | 553 |
| Uniprot | P47901, |
| Species.1 | Mouse |
| Gene ID.1 | 26361 |
| Uniprot.1 | Q9WU02, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P48974 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Lung carcinoma,Pituitary, |
| Signaling_pathway | Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction;Environmental Information Processing >> Signal transduction >> Calcium signaling pathway;Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway |
| Research Areas | >>Calcium signaling pathway; / >>Phospholipase D signaling pathway; / >>Neuroactive ligand-receptor interaction; / >>Vascular smooth muscle contraction |
| Function | Function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family., |
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