BEAN1 rabbit pAb
Ucallm_WP16240-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],
Specifications
| Size | 50μL/100μL |
| Target | BEAN1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BEAN1 AA range: 146-196 |
| Specificity | This antibody detects endogenous levels of BEAN1 at Human/Mouse |
| Gene Name | BEAN1 |
| Protein Name | BEAN1 |
| Other Name | |
| Species | Human |
| Gene ID | 146227 |
| Uniprot | Q3B7T3, |
| Species.1 | Mouse |
| Gene ID.1 | 65115 |
| Uniprot.1 | Q9EQG5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia |
| Research Areas | >>Spinocerebellar ataxia |
| Function | subunit:Interacts with NEDD4., |
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